Hydroa vacciniforme-like lymphoproliferative disorder in Korea

Hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) is a rare Epstein–Barr virus (EBV)-associated lymphoproliferative disease. The disease course of HVLPD varies from an indolent course to progression to aggressive lymphoma. We investigated the characteristics of HVLPD in Korean patients....

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Veröffentlicht in:Scientific reports 2020-11, Vol.10 (1), p.19294-19294, Article 19294
Hauptverfasser: Han, Byeol, Hur, Keunyoung, Ohn, Jungyoon, Kim, Tae Min, Jeon, Yoon Kyung, Kim, You Chan, Mun, Je-Ho
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Sprache:eng
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Zusammenfassung:Hydroa vacciniforme-like lymphoproliferative disorder (HVLPD) is a rare Epstein–Barr virus (EBV)-associated lymphoproliferative disease. The disease course of HVLPD varies from an indolent course to progression to aggressive lymphoma. We investigated the characteristics of HVLPD in Korean patients. HVLPD patients at Seoul National University Hospital between 1988 and 2019 were retrospectively analyzed. This study included 26 HVLPD patients who all presented with recurrent papulovesicular and necrotic eruption on the face, neck, and extremities. EBV was detected from the skin tissues of all patients. HVLPD was diagnosed during childhood (age
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-76345-2