“Chronic Disseminated Aspergillosis,” a Novel Fungal Immune Reconstitution Inflammatory Syndrome

Abstract We report a case of chronic hepatosplenic aspergillosis following immune reconstitution complicating colic aspergillosis in an AIDS patient with multicentric Castleman disease. Symptoms mimicked the clinical presentation of chronic disseminated candidiasis and responded to corticosteroid. T...

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Veröffentlicht in:	Open Forum Infectious Diseases 2020-11, Vol.7 (11), p.ofaa175-ofaa175
Hauptverfasser:	Pourbaix, Annabelle, Guery, Romain, Bruneau, Julie, Blanc, Estelle, Jouvion, Gregory, Weinandt, Marthe, Rouzaud, Claire, Lourenço, Jérémy, Boutboul, David, Mira, Jean-Paul, Rouquette, Alexandre, Molina, Thierry Jo, Lecuit, Marc, Lortholary, Olivier
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillosis Brief Reports Caspofungin Communicable diseases Corticosteroids Emtricitabine Enfuvirtide Fungi Highly active antiretroviral therapy Human health and pathology Immunology Infectious diseases Life Sciences Metronidazole Microbiology and Parasitology Mycology Organ transplant recipients Transplantation of organs, tissues, etc
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Zusammenfassung:	Abstract We report a case of chronic hepatosplenic aspergillosis following immune reconstitution complicating colic aspergillosis in an AIDS patient with multicentric Castleman disease. Symptoms mimicked the clinical presentation of chronic disseminated candidiasis and responded to corticosteroid. This emerging entity enlarges the spectrum of fungal immune reconstitution inflammatory syndrome in the HIV setting.
ISSN:	2328-8957 2328-8957
DOI:	10.1093/ofid/ofaa175