Headache: A striking prodromal and persistent symptom, predictive of COVID-19 clinical evolution

Headache: A striking prodromal and persistent symptom, predictive of COVID-19 clinical evolution

Objective To define headache characteristics and evolution in relation to COVID-19 and its inflammatory response. Methods This is a prospective study, comparing clinical data and inflammatory biomarkers of COVID-19 patients with and without headache, recruited at the Emergency Room. We compared base...

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Veröffentlicht in:Cephalalgia 2020-11, Vol.40 (13), p.1410-1421
Hauptverfasser: Caronna, Edoardo, Ballvé, Alejandro, Llauradó, Arnau, Gallardo, Victor José, Ariton, Diana María, Lallana, Sofia, López Maza, Samuel, Olivé Gadea, Marta, Quibus, Laura, Restrepo, Juan Luis, Rodrigo-Gisbert, Marc, Vilaseca, Andreu, Hernandez Gonzalez, Manuel, Martinez Gallo, Monica, Alpuente, Alicia, Torres-Ferrus, Marta, Pujol Borrell, Ricard, Alvarez-Sabin, José, Pozo-Rosich, Patricia
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Betacoronavirus
Biomarkers - blood
Coronavirus Infections - complications
Coronavirus Infections - immunology
COVID-19
Female
Headache - epidemiology
Headache - virology
Humans
Inflammation - blood
Inflammation - virology
Male
Middle Aged
Pandemics
Pneumonia, Viral - complications
Pneumonia, Viral - immunology
Prodromal Symptoms
Prospective Studies
SARS-CoV-2
Special Section
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Zusammenfassung:Objective To define headache characteristics and evolution in relation to COVID-19 and its inflammatory response. Methods This is a prospective study, comparing clinical data and inflammatory biomarkers of COVID-19 patients with and without headache, recruited at the Emergency Room. We compared baseline with 6-week follow-up to evaluate disease evolution. Results Of 130 patients, 74.6% (97/130) had headache. In all, 24.7% (24/97) of patients had severe pain with migraine-like features. Patients with headache had more anosmia/ageusia (54.6% vs. 18.2%; p 
ISSN:0333-1024
1468-2982
1468-2982
DOI:10.1177/0333102420965157