Bifacial stem cell niches in fish and plants

Highlights • The cambium in plants and the ciliary marginal zone (CMZ) in the vertebrate eye produce tissues in a bidirectional manner. • Homeobox transcription factors are key regulators of the cambium and the CMZ. • Intercellular signaling cascades are essential for the patterning of both the camb...

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Veröffentlicht in:Current opinion in genetics & development 2017-08, Vol.45, p.28-33
Hauptverfasser: Shi, Dongbo, Tavhelidse, Tinatini, Thumberger, Thomas, Wittbrodt, Joachim, Greb, Thomas
Format: Artikel
Sprache:eng
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Zusammenfassung:Highlights • The cambium in plants and the ciliary marginal zone (CMZ) in the vertebrate eye produce tissues in a bidirectional manner. • Homeobox transcription factors are key regulators of the cambium and the CMZ. • Intercellular signaling cascades are essential for the patterning of both the cambium and the CMZ. • The comparison of regulatory principles found in the cambium and the CMZ helps to reveal commonalities of bifacial stem cell niches.
ISSN:0959-437X
1879-0380
DOI:10.1016/j.gde.2017.02.002