Using CHADS2 and CHA2DS2-VASc scores for mortality prediction in patients with chronic kidney disease

Chronic kidney disease (CKD) is a public health issue and is associated with high morbidity and mortality. How to identify the high-risk CKD patients is very important to improve the long-term outcome. CHADS 2 and CHA2DS2-VASc scores are clinically useful scores to evaluate the risk of stroke in pat...

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Veröffentlicht in:Scientific reports 2020-11, Vol.10 (1), p.18942-18942, Article 18942
Hauptverfasser: Hsu, Po-Chao, Lee, Wen-Hsien, Chen, Szu-Chia, Tsai, Yi-Chun, Chen, Ying-Chih, Chu, Chun-Yuan, Lin, Tsung-Hsien, Voon, Wen-Chol, Lai, Wen-Ter, Sheu, Sheng-Hsiung, Su, Ho-Ming
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Sprache:eng
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Zusammenfassung:Chronic kidney disease (CKD) is a public health issue and is associated with high morbidity and mortality. How to identify the high-risk CKD patients is very important to improve the long-term outcome. CHADS 2 and CHA2DS2-VASc scores are clinically useful scores to evaluate the risk of stroke in patients with atrial fibrillation. However, there was no literature discussing about the usefulness of CHADS 2 and CHA2DS2-VASc scores for cardiovascular (CV) and all-cause mortality prediction in CKD patients. This longitudinal study enrolled 437 patients with CKD. CHADS 2 and CHA2DS2-VASc scores were calculated for each patient. CV and all-cause mortality data were collected for long-term outcome prediction. The median follow-up to mortality was 91 (25th–75th percentile: 59–101) months. There were 66 CV mortality and 165 all-cause mortality. In addition to age and heart rate, CHADS 2 and CHA 2 DS 2 -VASc scores (both P value 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-76098-y