Acute right ventricular failure: a novel presentation of methadone-induced cardiotoxicity

As methadone use increases, the potential for methadone-induced cardiotoxicity (MIC) may rise. We describe a case of acute right ventricular (RV) failure leading to cardiogenic shock after methadone overdose. This presentation was followed by full RV recovery. This previously undescribed presentatio...

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Veröffentlicht in:	BMJ case reports 2020-11, Vol.13 (11), p.e237168
Hauptverfasser:	Taha, Mohamad Badie, Dasa, Osama, Al-Ani, Mohammad, Taha, Omar B, Radhakrishnan, Nila S, Ahmed, Mustafa M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Acute coronary syndromes Acute Disease Antitussive Agents - adverse effects Blood pressure Cardiac arrhythmia Cardiomyopathy Cardiotoxicity cardiovascular system Case reports clinical diagnostic tests Drug dosages Drug Overdose - complications Drug Overdose - diagnosis Ejection fraction Female Heart failure Heart Failure - chemically induced Heart Failure - diagnosis Heart Failure - physiopathology Heart rate Humans Infections Medical diagnosis Medical imaging Metabolism Methadone - adverse effects Middle Aged Narcotics Oxygen saturation Pain Pulmonary arteries Pulmonary embolisms Sepsis Sinuses Tomography, X-Ray Computed toxicology Unusual Presentation of More Common Disease/Injury Ventricular Function, Right - drug effects
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Zusammenfassung:	As methadone use increases, the potential for methadone-induced cardiotoxicity (MIC) may rise. We describe a case of acute right ventricular (RV) failure leading to cardiogenic shock after methadone overdose. This presentation was followed by full RV recovery. This previously undescribed presentation highlights the challenges involved with MIC, its diagnosis and its management.
ISSN:	1757-790X 1757-790X
DOI:	10.1136/bcr-2020-237168