Pulmonary function in extremely low birth weight infants with bronchopulmonary dysplasia before hospital discharge

Pulmonary function in extremely low birth weight infants with bronchopulmonary dysplasia before hospital discharge

Objective To compare pulmonary function in extremely low birth weight (ELBW) infants with bronchopulmonary dysplasia (BPD) studied at 34–36 weeks postmenstrual age (PMA) with a reference group of “healthy” infants born at 34–36 weeks. We hypothesized that ELBW infants have decreased functional resid...

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Veröffentlicht in:Journal of perinatology 2021-01, Vol.41 (1), p.77-83
Hauptverfasser: McEvoy, Cindy T., Schilling, Diane, Go, Mitzi D., Mehess, Shawn, Durand, Manuel
Format: Artikel
Sprache:eng
Schlagworte:
631/136/1425
692/308/409
Birth weight
Birth weight, Low
Bronchopulmonary dysplasia
Dysplasia
Health aspects
Infants
Infants (Premature)
Low-birth-weight
Lung diseases
Medicine
Medicine & Public Health
Patient outcomes
Pediatric research
Pediatric Surgery
Pediatrics
Pulmonary functions
Pulmonary ventilation
Respiratory function
Weight
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Zusammenfassung:Objective To compare pulmonary function in extremely low birth weight (ELBW) infants with bronchopulmonary dysplasia (BPD) studied at 34–36 weeks postmenstrual age (PMA) with a reference group of “healthy” infants born at 34–36 weeks. We hypothesized that ELBW infants have decreased functional residual capacity (FRC) and respiratory compliance (Crs). Study design Pulmonary function testing was performed at 34–36 weeks PMA in infants with BPD and within 96 h of age in infants delivered at 34–36 weeks. Results Twenty BPD patients and 20 healthy infants were studied. FRC (18.9 versus 26.2 mL/kg; adjusted 95% CI 5.0, 10.9; P  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-020-00856-z