Hyperprolactinemia in clinical non-functional pituitary macroadenomas: A STROBE-compliant study

Hyperprolactinemia in clinical non-functional pituitary macroadenomas: A STROBE-compliant study

Hyperprolactinemia is a prevalent endocrine disorder presented in patients with non-functional pituitary adenomas (NFPAs). However, the mechanism involved in hyperprolactinemia in NFPA is not fully illustrated. The current study aims to investigate predictors for hyperprolactinemia in NFPA via analy...

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Veröffentlicht in:Medicine (Baltimore) 2020-10, Vol.99 (41), p.e22673-e22673
Hauptverfasser: Lyu, Liang, Yin, Senlin, Hu, Yu, Chen, Cheng, Jiang, Yong, Yu, Yang, Ma, Weichao, Wang, Zeming, Jiang, Shu, Zhou, Peizhi
Format: Artikel
Sprache:eng
Schlagworte:
Adenoma - complications
Adenoma - surgery
Adult
Female
Humans
Hyperprolactinemia - etiology
Male
Middle Aged
Observational Study
Pituitary Neoplasms - complications
Pituitary Neoplasms - surgery
Retrospective Studies
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Zusammenfassung:Hyperprolactinemia is a prevalent endocrine disorder presented in patients with non-functional pituitary adenomas (NFPAs). However, the mechanism involved in hyperprolactinemia in NFPA is not fully illustrated. The current study aims to investigate predictors for hyperprolactinemia in NFPA via analyzing relevant clinical features. Thus, in this study, a cohort of 214 cases with integrated medical records was retrospectively analyzed concerning clinical, pathological, and endocrinological studies before and after surgery.Hyperprolactinemia happened in 93 cases (43.5%). Women (adjust odds ratio [OR] = 3.093; P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000022673