Utilization of serum procalcitonin as a biomarker in the diagnosis and treatment of children with bacterial hospital-acquired pneumonia

Utilization of serum procalcitonin as a biomarker in the diagnosis and treatment of children with bacterial hospital-acquired pneumonia

Hospital-acquired pneumonia (HAP) is one of the common infections in hospitalized patients. Early and prompt diagnosis of HAP is important because it aids in the appropriate selection of antibiotics and decreases the mortality and morbidity of patients. The investigation on serum procalcitonin (PCT)...

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Veröffentlicht in:Molecular and cellular biochemistry 2021-01, Vol.476 (1), p.261-267
Hauptverfasser: Wang, Wenlong, Zhu, Yitang, Yin, Linlin, Deng, Yaoyao, Chu, Guoxian, Liu, Supin
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Antibiotics
Bacteria
Biochemistry
Biomarkers
Biomedical and Life Sciences
C-reactive protein
Cardiology
Children
Correlation analysis
Diagnosis
Health aspects
Hospital patients
Inflammation
Leukocytes
Leukocytes (neutrophilic)
Life Sciences
Medical Biochemistry
Medical diagnosis
Medical research
Medicine, Experimental
Microbiology
Morbidity
Neutrophils
Oncology
Pathogens
Patients
Pediatrics
Pneumonia
Procalcitonin
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Zusammenfassung:Hospital-acquired pneumonia (HAP) is one of the common infections in hospitalized patients. Early and prompt diagnosis of HAP is important because it aids in the appropriate selection of antibiotics and decreases the mortality and morbidity of patients. The investigation on serum procalcitonin (PCT) levels in pediatric patients is limited. Herein we aimed to evaluate the role of PCT in the early diagnosis of children with bacterial HAP. The study enrolled 264 children (
ISSN:0300-8177
1573-4919
DOI:10.1007/s11010-020-03902-8