Recognising the asymptomatic enemy
Using a 36-gene RT-PCR assay, McClain and colleagues could identify differential transcription patterns in infected patients up to 3 days before the development of clinical signs, with an area under the receiver operating characteristic curve of 0·77. [...]they are unable to detect infection of inac...
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Veröffentlicht in: | The Lancet infectious diseases 2021-03, Vol.21 (3), p.305-306 |
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creator | Cebey-López, Miriam Salas, Antonio |
description | Using a 36-gene RT-PCR assay, McClain and colleagues could identify differential transcription patterns in infected patients up to 3 days before the development of clinical signs, with an area under the receiver operating characteristic curve of 0·77. [...]they are unable to detect infection of inaccessible anatomical sites. [...]detecting a particular microorganism does not imply disease causality; another undetected microorganism might be the cause of symptoms. |
doi_str_mv | 10.1016/S1473-3099(20)30587-9 |
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subjects | Antibiotics Asymptomatic Bacterial infections Biological Evolution Comment Epidemics Gene Expression Humans Infections Infectious diseases Microorganisms Mortality Pandemics Pathogens Polymerase chain reaction Prospective Studies Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Signs and symptoms Transcription Viral infections Viruses |
title | Recognising the asymptomatic enemy |
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