Continuous Glucose Monitoring and Use of Alternative Markers To Assess Glycemia in Chronic Kidney Disease

In chronic kidney disease, glycated albumin and fructosamine have been postulated to be better biomarkers of glycemic control than HbA . We evaluated the accuracy, variability, and covariate bias of three biomarkers (HbA , glycated albumin, and fructosamine) compared with continuous glucose monitori...

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Veröffentlicht in:Diabetes care 2020-10, Vol.43 (10), p.2379-2387
Hauptverfasser: Zelnick, Leila R, Batacchi, Zona O, Ahmad, Iram, Dighe, Ashveena, Little, Randie R, Trence, Dace L, Hirsch, Irl B, de Boer, Ian H
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Sprache:eng
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Zusammenfassung:In chronic kidney disease, glycated albumin and fructosamine have been postulated to be better biomarkers of glycemic control than HbA . We evaluated the accuracy, variability, and covariate bias of three biomarkers (HbA , glycated albumin, and fructosamine) compared with continuous glucose monitoring (CGM)-derived measurement of glycemia across estimated glomerular filtration rate (eGFR) in type 2 diabetes. A prospective cohort study was conducted of 104 participants with type 2 diabetes, 80 with eGFR
ISSN:0149-5992
1935-5548
DOI:10.2337/dc20-0915