Antimicrobial resistance profiles of ESKAPE and Escherichia coli isolated from blood at a tertiary hospital in China

[2] The frequencies and resistance rates of ESKAPE and E. coli are most likely interrelated with the spectrum of disease, geographical situation, antimicrobial management, and hand hygiene. Since 2012, some requirements have been gradually executed according to the Measures for the Administration of Clinical Application of Antibiotics (Decree No. 84 of the Ministry of Health), the Guidelines for Clinical Application of Antibiotics (2015 edition), and the Notice on Continuous Management of Clinical Application of Antibiotics (General Office of the National Health Commission, 2018) at our hospital. [...]proportions of vancomycin-resistant E. faecium isolated from patients with BSIs have increased since 2012 in Europe,[5] indicating a geographic difference for vancomycin-resistant Enterococcus (VRE). [...]E. faecium resistance should be evaluated regularly, although VRE was not detected at our hospital during the study period. [...]ARI could be a significant indicator of the antibiotic resistance.