Video-assisted thoracoscopic lobectomy is feasible for selected patients with clinical N2 non-small cell lung cancer

Few studies have evaluated the usefulness of video-assisted thoracoscopic surgery (VATS) for advanced-stage lung cancer. We aimed to evaluate the feasibility of VATS for treating clinical N2 (cN2) lung cancer. A retrospective cohort analysis was performed with data from 268 patients who underwent lo...

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Veröffentlicht in:	Scientific reports 2020-09, Vol.10 (1), p.15217-15217, Article 15217
Hauptverfasser:	Yun, Jae Kwang, Lee, Geun Dong, Choi, Sehoon, Kim, Hyeong Ryul, Kim, Yong-Hee, Park, Seung-Il, Kim, Dong Kwan
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4028/546 692/699/67/1612/1350 Aged Carcinoma, Non-Small-Cell Lung - pathology Carcinoma, Non-Small-Cell Lung - surgery Feasibility Studies Female Humanities and Social Sciences Humans Length of Stay Lung cancer Lung Neoplasms - pathology Lung Neoplasms - surgery Lymph nodes Male Middle Aged multidisciplinary Neoplasm Staging Non-small cell lung carcinoma Ostomy Patients Pneumonectomy - methods Propensity Score Retrospective Studies Science Science (multidisciplinary) Small cell lung carcinoma Surgery Survival Survival Analysis Thoracic Surgery, Video-Assisted - methods Thoracotomy - methods Treatment Outcome Tumors
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Zusammenfassung:	Few studies have evaluated the usefulness of video-assisted thoracoscopic surgery (VATS) for advanced-stage lung cancer. We aimed to evaluate the feasibility of VATS for treating clinical N2 (cN2) lung cancer. A retrospective cohort analysis was performed with data from 268 patients who underwent lobectomy for cN2 disease from 2007 to 2016. Using propensity score-based inverse probability of treatment weighting (IPTW), perioperative and long-term survival outcomes were compared. We performed VATS and open thoracotomy on 121 and 147 patients, respectively. Overall, VATS was preferred for patients with peripherally located tumors ( p
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-020-72272-4