A life‐time of hazardous drinking and harm to health among older adults: findings from the Whitehall II prospective cohort study

Aims To investigate associations of life‐time hazardous and binge drinking with biomarkers of cardiometabolic health, liver function, cardiovascular disease (CVD) and mortality. Design Prospective cohort study with median follow‐up time to CVD incidence of 4.5 years. Setting London, UK: civil servan...

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Veröffentlicht in:Addiction (Abingdon, England) England), 2020-10, Vol.115 (10), p.1855-1866
Hauptverfasser: Ng Fat, Linda, Bell, Steven, Britton, Annie
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Sprache:eng
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Zusammenfassung:Aims To investigate associations of life‐time hazardous and binge drinking with biomarkers of cardiometabolic health, liver function, cardiovascular disease (CVD) and mortality. Design Prospective cohort study with median follow‐up time to CVD incidence of 4.5 years. Setting London, UK: civil servants within the Whitehall II Study. Participants A total of 4820 drinkers aged 59–83 years with biological measurements during the 2011–12 survey. Measurements Hazardous drinking was defined as having an AUDIT‐C score ≥ 5 calculated at each decade of life, forming the following groups: never hazardous drinker, former early (stopping before age 50), former later (stopping after age 50), current hazardous drinker and consistent hazardous drinker (hazardous drinker at each decade of life). Findings More than half the sample had been hazardous drinkers at some point during their life‐time, comprising former early (
ISSN:0965-2140
1360-0443
1360-0443
DOI:10.1111/add.15013