Association between Neutrophil Percentage-to-Albumin Ratio and All-Cause Mortality in Critically Ill Patients with Coronary Artery Disease

Association between Neutrophil Percentage-to-Albumin Ratio and All-Cause Mortality in Critically Ill Patients with Coronary Artery Disease

Background. Neutrophil percentage-to-albumin ratio (NPAR) has been proved to be associated with clinical outcome of many diseases. This study was aimed at exploring the independent effect of NPAR on all-cause mortality of critically ill patients with coronary artery disease (CAD). Method. NPAR was c...

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Veröffentlicht in:BioMed research international 2020, Vol.2020, p.8137576-12
Hauptverfasser: Sun, Tienan, Shen, Hua, Guo, Qianyun, Yang, Jiaqi, Zhai, Guangyao, Zhang, Jingrui, Zhang, Biyang, Ding, Yaodong, Cai, Chenghui, Zhou, Yujie
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Sprache:eng
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Age
Aged
Aged, 80 and over
Albumin
Anticoagulants
Atherosclerosis
Beta blockers
Biomedical research
Blood platelets
Blood pressure
Body mass index
Cardiovascular disease
Cholesterol
Chronic obstructive pulmonary disease
Clinical outcomes
Coronary artery
Coronary artery disease
Coronary Artery Disease - blood
Coronary Artery Disease - mortality
Coronary Artery Disease - pathology
Critical Illness - mortality
Demographics
Diabetes
Ethnicity
Female
Gender
Heart attacks
Heart diseases
Hemoglobin
Humans
Hypertension
Inflammation
Intensive care
Kaplan-Meier Estimate
Laboratories
Male
Middle Aged
Mortality
Neutrophils - metabolism
Neutrophils - pathology
Patients
Percutaneous Coronary Intervention
Prognosis
Proportional Hazards Models
Risk Factors
Serum albumin
Serum Albumin - metabolism
Statistical analysis
Statistical models
Subgroups
Vital signs
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Zusammenfassung:Background. Neutrophil percentage-to-albumin ratio (NPAR) has been proved to be associated with clinical outcome of many diseases. This study was aimed at exploring the independent effect of NPAR on all-cause mortality of critically ill patients with coronary artery disease (CAD). Method. NPAR was calculated as neutrophil percentage numerator divided by serum albumin concentration. Clinical endpoints were 30-day, 90-day, and 365-day all-cause mortality. Multivariable Cox proportional hazard models were performed to confirm the association between NPAR and all-cause mortality. Result. 3106 patients with CAD were enrolled. All-cause mortality rates of 30 days (P
ISSN:2314-6133
2314-6141
DOI:10.1155/2020/8137576