Patientenantikörper als Informationsquelle

Since decades antibodies are used for diagnosis e. g. by detecting patient antibodies that specifically bind to Influenza virus proteins. We predict these diagnostic questions will be parallelized to diagnose all known disease specific antibodies at once. These tests will ask in addition, which unkn...

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Veröffentlicht in:Biospektrum 2020-09, Vol.26 (5), p.556-558
Hauptverfasser: Falk, Fabian, Zhou, Zekun, Klinkusch, Andreas, Weber, Laura, Breitling, Frank
Format: Artikel
Sprache:eng ; ger
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Zusammenfassung:Since decades antibodies are used for diagnosis e. g. by detecting patient antibodies that specifically bind to Influenza virus proteins. We predict these diagnostic questions will be parallelized to diagnose all known disease specific antibodies at once. These tests will ask in addition, which unknown antibodies patrol in a patient’s blood, and what exactly they bind to. Thereby, we expect to find antibody species that correlate to hitherto enigmatic diseases or have specialized functions.
ISSN:0947-0867
1868-6249
DOI:10.1007/s12268-020-1440-0