Safety‐net versus private hospital setting for brain metastasis patients treated with radiosurgery alone: Disparities in follow‐up care and outcomes

BACKGROUND Stereotactic radiosurgery (SRS) alone is an increasingly accepted treatment for brain metastases, but it requires adherence to frequently scheduled follow‐up neuroimaging because of the risk of distant brain metastasis. The effect of disparities in access to follow‐up care on outcomes after SRS alone is unknown. METHODS This retrospective study included 153 brain metastasis patients treated consecutively with SRS alone from 2010 through 2016 at an academic medical center and a safety‐net hospital (SNH) located in Los Angeles, California. Outcomes included neurologic symptoms, hospitalization, steroid use and dependency, salvage SRS, salvage whole‐brain radiotherapy, salvage neurosurgery, and overall survival. RESULTS Ninety‐three of the 153 patients were private hospital (PH) patients, and 60 were SNH patients. The median follow‐up time was 7.7 months. SNH patients received fewer follow‐up neuroimaging studies (1.5 vs 3; P = .008). In a multivariate analysis, the SNH setting was a significant risk factor for salvage neurosurgery (hazard ratio [HR], 13.65; P