Multiple sclerosis, human herpesvirus 4 and thyroid collision tumor: A case report

The role of interferon [beta]-1b (IFN[beta]-1b), used for multiple sclerosis (MS) therapy, in cancer occurrence is uncertain. There is evidence supporting the role of human herpesvirus 4 [Epstein-Barr virus (EBV)] in thyroid cancer and MS. Simultaneous occurrence of papillary and medullary carcinoma...

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Veröffentlicht in:Experimental and therapeutic medicine 2020-10, Vol.20 (4), p.3458-3461
Hauptverfasser: Sirbu, Anca Maria, Sirbu, Carmen Adella, Eftimie, Lucian, Soare, Angela Mirela, Ghinescu, Minerva Claudia, Ionita- Radu, Florentina
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Sprache:eng
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Zusammenfassung:The role of interferon [beta]-1b (IFN[beta]-1b), used for multiple sclerosis (MS) therapy, in cancer occurrence is uncertain. There is evidence supporting the role of human herpesvirus 4 [Epstein-Barr virus (EBV)] in thyroid cancer and MS. Simultaneous occurrence of papillary and medullary carcinomas is rare, and its association with MS in a young woman raises questions. A 46-year-old female patient was diagnosed with relapsing-remitting multiple sclerosis in 2008. In 2018, cervical MRI detected a thyroid nodule with right cervical adenopathy. Her thyroid function was normal, but increased calcitonin levels were found (70.53 pg/ml; normal value:
ISSN:1792-0981
1792-1015
DOI:10.3892/etm.2020.8975