IDH Mutations in AML Patients; A higher Association with Intermediate Risk Cytogenetics

IDH mutations diversely affect the prognosis of cyogenetically normal acute myeloid leukemia (CN-AML) adult patients. The aim of this study is to assess the frequency of IDH mutations and to evaluate its role in AML prognosis. We have analyzed IDH1 and 2 mutations using High Resolution Melting curve...

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Veröffentlicht in:	Asian Pacific Journal of Cancer Prevention 2020-03, Vol.21 (3), p.721-725
Hauptverfasser:	ElNahass, Yasser H, Badawy, Ragia H, ElRefaey, Fatma A, Nooh, Hend A, Ibrahiem, Dalia, Nader, Heba A, Mahmoud, Hossam K, ElMetnawy, Wafaa H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Female Humans Isocitrate Dehydrogenase - genetics Karyotyping Leukemia, Myeloid, Acute - genetics Male Middle Aged Mutation Risk Factors Young Adult
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