Neutrophil to lymphocyte ratio and breast cancer risk: analysis by subtype and potential interactions

Neutrophil to lymphocyte ratio and breast cancer risk: analysis by subtype and potential interactions

Multiple studies have found the neutrophil to lymphocyte ratio (NLR) to be associated with adverse breast cancer (BC) prognosis and survival. Very limited data exist on the role of NLR and risk of BC. The BREOGAN study is a population-based case–control study conducted in Galicia, Spain. We examined...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Scientific reports 2020-08, Vol.10 (1), p.13203-13203, Article 13203
Hauptverfasser: Gago-Dominguez, Manuela, Matabuena, Marcos, Redondo, Carmen M., Patel, Sandip Pravin, Carracedo, Angel, Ponte, Sara Miranda, Martínez, María Elena, Castelao, J. Esteban
Format: Artikel
Sprache:eng
Schlagworte:
631/45/608
631/67/1347
692/4028/67/1347
692/53
Adolescent
Adult
Breast cancer
Breast Neoplasms - blood
Breast Neoplasms - epidemiology
Breast Neoplasms - pathology
Case-Control Studies
Child
Cholesterol
ErbB-2 protein
Female
Health risks
Humanities and Social Sciences
Humans
Hydrogen peroxide
Leukocytes (neutrophilic)
Lymphocyte Count
Lymphocytes
Lymphocytes - cytology
Medical prognosis
Menopause
Middle Aged
multidisciplinary
Neoplasm Grading
Neoplasm Staging
Neutrophils
Neutrophils - cytology
Population studies
Pregnancy
Risk
Risk reduction
Science
Science (multidisciplinary)
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Multiple studies have found the neutrophil to lymphocyte ratio (NLR) to be associated with adverse breast cancer (BC) prognosis and survival. Very limited data exist on the role of NLR and risk of BC. The BREOGAN study is a population-based case–control study conducted in Galicia, Spain. We examined the WBC- and NLR-BC relationships. The risk of BC increased with increasing levels of neutrophils percentage (NE%) (multivariable OR for the highest category (95% CI) = 2.14 (1.39–3.32), P-trend 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-70077-z