Cognitive Impairment, Chronic Kidney Disease, and 1-Year Mortality in Older Patients Discharged from Acute Care Hospital

Cognitive Impairment, Chronic Kidney Disease, and 1-Year Mortality in Older Patients Discharged from Acute Care Hospital

The prognostic interaction between chronic kidney disease (CKD) and cognitive impairment is still to be elucidated. We investigated the potential interaction of overall cognitive impairment or defective constructional praxis and CKD in predicting 1-year mortality among 646 older patients discharged...

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Veröffentlicht in:Journal of clinical medicine 2020-07, Vol.9 (7), p.2202
Hauptverfasser: Di Rosa, Mirko, D'Alia, Sonia, Guarasci, Francesco, Soraci, Luca, Pierpaoli, Elisa, Lenci, Federica, Ricci, Maddalena, Onder, Graziano, Volpato, Stefano, Ruggiero, Carmelinda, Cherubini, Antonio, Corsonello, Andrea, Lattanzio, Fabrizia
Format: Artikel
Sprache:eng
Schlagworte:
Age
Anemia
Cardiovascular disease
Caregivers
Clinical medicine
Cognitive ability
Comorbidity
Coronary vessels
Creatinine
Delirium
Dementia
Diabetes
Gender
Geriatrics
Heart failure
Hospitals
Kidney diseases
Mortality
Older people
Polypharmacy
Regression analysis
Vein & artery diseases
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Zusammenfassung:The prognostic interaction between chronic kidney disease (CKD) and cognitive impairment is still to be elucidated. We investigated the potential interaction of overall cognitive impairment or defective constructional praxis and CKD in predicting 1-year mortality among 646 older patients discharged from hospital. The estimated glomerular filtration rate (eGFR) was calculated using the Berlin Initiative Study (BIS) equation. Cognitive impairment was assessed by the Mini Mental State Exam (MMSE) and defective constructional praxis was ascertained by the inherent MMSE item. The study outcome was 1-year mortality. Statistical analysis was carried out using Cox regression. After adjusting for potential confounders, the co-occurrence of eGFR
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm9072202