Circulating Progenitor Cells are Positively Associated with Cognitive Function Among Overweight/Obese Children

Highlights • We compared the quantity of circulating progenitor cells and inflammatory monocytes in overweight/obese and healthy weight children, and related these quantities to cognition, and neurogenesis in vitro. • Higher concentrations of circulating progenitor cells and inflammatory monocytes w...

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Veröffentlicht in:Brain, behavior, and immunity behavior, and immunity, 2016-10, Vol.57, p.47-52
Hauptverfasser: Niemiro, Grace M, Raine, Lauren B, Khan, Naiman A, Emmons, Russell, Little, Jonathan, Kramer, Arthur F, Hillman, Charles H, Lisio, Michael De
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Sprache:eng
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Zusammenfassung:Highlights • We compared the quantity of circulating progenitor cells and inflammatory monocytes in overweight/obese and healthy weight children, and related these quantities to cognition, and neurogenesis in vitro. • Higher concentrations of circulating progenitor cells and inflammatory monocytes were observed in the overweight/obese children. • Differential relationships exist between circulating progenitor cells and executive processing between overweight/obese and healthy weight children. • Secretome of overweight/obese circulating progenitor cells caused a trend for an increase in neuroblast viability in vitro.
ISSN:0889-1591
1090-2139
DOI:10.1016/j.bbi.2016.03.018