COVID‐19 and hydatidiform mole

The emergence of coronavirus disease 2019 (COVID‐19) as a pandemic threatens the entire world resulting in severe consequences for people's health. Pregnant patients with COVID‐19 had immune dysregulation that could result in abnormal pregnancy outcomes such as hydatidiform mole (HM), recurrent...

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Veröffentlicht in:	American journal of reproductive immunology (1989) 2020-11, Vol.84 (5), p.e13310-n/a
Hauptverfasser:	Abbas, Ahmed M., Ahmed, Lobna, Salem, Amera S., Elsamman, Shimaa H., Refai, Alshaima, Fathy, Safaa K., Ahmed, Omar A., Shalotut, Asmaa S., AbdelWahab, Radwa A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - metabolism coronavirus Coronaviruses COVID-19 COVID-19 - immunology Cytokines Cytokines - metabolism Female Gestational trophoblastic diseases Humans Hydatidiform mole Hydatidiform Mole - immunology Leukocytes Leukocytes - immunology Pandemics Pre-eclampsia Pregnancy Pregnancy Complications, Infectious - immunology Pregnancy Outcome Pyrin protein SARS-CoV-2 - physiology Special Issue
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Zusammenfassung:	The emergence of coronavirus disease 2019 (COVID‐19) as a pandemic threatens the entire world resulting in severe consequences for people's health. Pregnant patients with COVID‐19 had immune dysregulation that could result in abnormal pregnancy outcomes such as hydatidiform mole (HM), recurrent pregnancy loss, and early‐onset preeclampsia. In this article, we tried to summarize the possible association between COVID‐19 and the HM's development by reviewing the role of NOD‐Like Receptor (NLR) Family Pyrin Domain Containing 7 (NLRP7), cytokines, zinc, and leukocytes in the pathogenesis of HM.
ISSN:	1046-7408 1600-0897
DOI:	10.1111/aji.13310