Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop

Pediatric Extrapolation in Type 2 Diabetes: Future Implications of a Workshop

Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan...

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Veröffentlicht in:Clinical pharmacology and therapeutics 2020-07, Vol.108 (1), p.29-39
Hauptverfasser: Barrett, Jeffrey S., Bucci‐Rechtweg, Christina, Amy Cheung, S. Y., Gamalo‐Siebers, Margaret, Haertter, Sebastian, Karres, Janina, Marquard, Jan, Mulugeta, Yeruk, Ollivier, Cecile, Strougo, Ashley, Yanoff, Lisa, Yao, Lynne, Zeitler, Philip
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Age Factors
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - epidemiology
Diabetes Mellitus, Type 2 - physiopathology
Disease Progression
Education - methods
Humans
Hypoglycemic Agents - pharmacology
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Zusammenfassung:Extrapolation from adults to youth with type 2 diabetes (T2D) is challenged by differences in disease progression and manifestation. This manuscript presents the results of a mock‐team workshop focused on examining the typical team‐based decision process used to propose a pediatric development plan for T2D addressing the viability of extrapolation. The workshop was held at the American Society for Clinical Pharmacology and Therapeutics (ASCPT) in Orlando, Florida on March 21, 2018.
ISSN:0009-9236
1532-6535
DOI:10.1002/cpt.1805