Downregulation of LUZP2 Is Correlated with Poor Prognosis of Low-Grade Glioma

Background. LUZP2 is a protein limitedly expressed in the brain and spinal cord, while there are few studies on it in brain tumors. Low-grade glioma (LGG) is one of the most common brain tumors. However, the biological behavior of LGG is not very clear at present. This study was aimed at exploring t...

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Veröffentlicht in:	BioMed research international 2020, Vol.2020 (2020), p.1-16
Hauptverfasser:	Chen, Qianxue, Liu, Baohui, Geng, Rongxin, Jiang, Hongxiang, Zhang, Huikai, Qi, Yangzhi, Deng, Gang, Li, Yong, Ye, Zhang
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Biomarkers Brain Brain cancer Brain Neoplasms - genetics Brain Neoplasms - pathology Brain tumors Data bases Data mining Datasets DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Down-Regulation - genetics Extracellular matrix Gender Gene expression Gene Expression Regulation, Neoplastic Gene Ontology Gene Regulatory Networks Genes Genomes Glioma Glioma - genetics Glioma - pathology Gliomas Histology Humans Intellectual disabilities Kaplan-Meier Estimate Medical prognosis Metabolic pathways MicroRNAs - genetics MicroRNAs - metabolism Multivariate analysis Neoplasm Grading Nervous system Patients Prognosis Proportional Hazards Models Prostate cancer Radiation therapy Regulatory mechanisms (biology) RNA, Messenger - genetics RNA, Messenger - metabolism Spinal cord Survival Analysis Transcription factors Transcription Factors - metabolism Tumors Up-Regulation - genetics
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