Added value of chest computed tomography in suspected COVID-19: an analysis of 239 patients

Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, clinicians have been struggling with the optimal diagnostic approach of suspected patients. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) testing of respiratory samples is generally being considered as the r...

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Veröffentlicht in:The European respiratory journal 2020-08, Vol.56 (2), p.2001377
Hauptverfasser: Korevaar, Daniël A, Kootte, Ruud S, Smits, Loek P, van den Aardweg, Joost G, Bonta, Peter I, Schinkel, Janke, Vigeveno, René M, van den Berk, Inge A H, Scheerder, Maeke J, Lemkes, Bregtje A, Goorhuis, Abraham, Beenen, Ludo F M, Annema, Jouke T
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Sprache:eng
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Zusammenfassung:Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, clinicians have been struggling with the optimal diagnostic approach of suspected patients. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) testing of respiratory samples is generally being considered as the reference standard for establishing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection [1]. However, RT-PCR results take hours to become available and, although highly specific, sensitivity is moderate [2–4]. This could result in delayed and suboptimal clinical decision making. In a high-prevalence emergency department setting, chest CT showed a high probability of COVID-19 in 30% of patients with a negative or indeterminate initial RT-PCR result https://bit.ly/38hLDzR
ISSN:0903-1936
1399-3003
DOI:10.1183/13993003.01377-2020