Recent Progress in Steroid Synthesis Triggered by the Emergence of New Catalytic Methods

The rich biology associated with steroids dictates a growing demand for the new synthetic strategies that would improve the access to natural and unnatural representatives of this family. The recent advances in the field of catalysis have greatly impacted the field of natural product synthesis inclu...

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Veröffentlicht in:European journal of organic chemistry 2020-02, Vol.2020 (7), p.755-776
Hauptverfasser: Khatri, Hem Raj, Carney, Nolan, Rutkoski, Ryan, Bhattarai, Bijay, Nagorny, Pavel
Format: Artikel
Sprache:eng
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Zusammenfassung:The rich biology associated with steroids dictates a growing demand for the new synthetic strategies that would improve the access to natural and unnatural representatives of this family. The recent advances in the field of catalysis have greatly impacted the field of natural product synthesis including the synthesis of steroids. This article provides a short overview of the recent progress in the synthesis of steroids that was enabled by the advances in catalysis. This mini review discusses the recent progress in the synthesis of steroids that was enabled by the advances in the transition metal catalysis, Lewis acid catalysis and organocatalysis.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.201901466