Sex differences in eligibility for advanced heart failure therapies

Objectives We investigated sex‐based differences in eligibility for and outcomes after receipt of advanced heart failure (HF) therapies. Background Although women are more likely to die from HF than men, registry data suggest that women are less likely to receive heart transplant (HT) or left ventri...

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Veröffentlicht in:Clinical transplantation 2020-05, Vol.34 (5), p.e13839-n/a
Hauptverfasser: Steinberg, Rebecca S., Nayak, Aditi, O'Connell, Celena, Burford, Sharon, Pekarek, Ann, Chesnut, Neile, Cole, Robert T., Gupta, Divya, Laskar, S. Raja, Bhatt, Kunal, Burke, Michael, Attia, Tamer, Smith, Andrew, Vega, J. David, Morris, Alanna A.
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Sprache:eng
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Zusammenfassung:Objectives We investigated sex‐based differences in eligibility for and outcomes after receipt of advanced heart failure (HF) therapies. Background Although women are more likely to die from HF than men, registry data suggest that women are less likely to receive heart transplant (HT) or left ventricular assist device (LVAD) for largely unknown reasons. Methods We performed a single‐center retrospective cohort study of patients evaluated for advanced HF therapies from 2012 to 2016. Logistic regression was used to determine the association of sex with eligibility for HT/LVAD. Competing risks and Kaplan‐Meier analysis were used to examine survival. Results Of 569 patients (31% women) evaluated, 223 (39.2%) were listed for HT and 81 (14.2%) received destination (DT) LVAD. Women were less likely to be listed for HT (adjusted odds ratio [OR] 0.36, 95% confidence interval [CI] 0.21‐0.61; P 
ISSN:0902-0063
1399-0012
DOI:10.1111/ctr.13839