Treatment Patterns of Lipid-Lowering Therapy in Patients with Coronary Artery Disease Aged Above and Below 75 Years: A Retrospective Cross-Sectional Study of 1500 Patients in a Tertiary Care Referral Center in Germany

Introduction Lipid-lowering therapy of elderly patients with coronary artery disease (CAD) inherits a medical challenge, as these patients experience a higher absolute risk reduction but may be more prone to side effects. We aimed to evaluate the treatment patterns in lipid-lowering therapy, compari...

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Veröffentlicht in:Drugs & aging 2020-07, Vol.37 (7), p.521-527
Hauptverfasser: Dykun, Iryna, Wiefhoff, Daniela, Totzeck, Matthias, Al-Rashid, Fadi, Jánosi, R. Alexander, Hendricks, Stefanie, Rassaf, Tienush, Mahabadi, Amir A.
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Sprache:eng
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Zusammenfassung:Introduction Lipid-lowering therapy of elderly patients with coronary artery disease (CAD) inherits a medical challenge, as these patients experience a higher absolute risk reduction but may be more prone to side effects. We aimed to evaluate the treatment patterns in lipid-lowering therapy, comparing CAD patients above versus below 75 years of age. Methods We retrospectively included patients with known CAD admitted to the West German Heart and Vascular Center. Low-density lipoprotein cholesterol (LDL-C) levels and intensity of statin therapy (based on dosage and type of statin) were assessed from all available hospital records. Results We included 1500 patients (mean age 68.4 ± 11.2 years, 75.7% male) from 813 referring treating primary care physicians in 98 cities of Germany in our analysis. A total of 982 patients were
ISSN:1170-229X
1179-1969
DOI:10.1007/s40266-020-00768-9