Reduction of Coronavirus Burden With Mass Azithromycin Distribution

Reduction of Coronavirus Burden With Mass Azithromycin Distribution

Abstract We evaluated the potential antiviral effects of azithromycin on the nasopharyngeal virome of Nigerien children who had received multiple rounds of mass drug administration. We found that the respiratory burden of non–severe acute respiratory syndrome coronaviruses was decreased with azithro...

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Veröffentlicht in:Clinical infectious diseases 2020-11, Vol.71 (16), p.2282-2284
Hauptverfasser: Doan, Thuy, Hinterwirth, Armin, Arzika, Ahmed M, Worden, Lee, Chen, Cindi, Zhong, Lina, Oldenburg, Catherine E, Keenan, Jeremy D, Lietman, Thomas M
Format: Artikel
Sprache:eng
Schlagworte:
Administration, Oral
Antiviral Agents - administration & dosage
Antiviral Agents - therapeutic use
Azithromycin - administration & dosage
Azithromycin - therapeutic use
Brief Reports
Child, Preschool
Coronavirus - drug effects
Coronavirus Infections - drug therapy
Coronavirus Infections - mortality
Humans
Infant
Infant, Newborn
Mass Drug Administration
Nasopharynx - virology
Nigeria - epidemiology
Viral Load - drug effects
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Zusammenfassung:Abstract We evaluated the potential antiviral effects of azithromycin on the nasopharyngeal virome of Nigerien children who had received multiple rounds of mass drug administration. We found that the respiratory burden of non–severe acute respiratory syndrome coronaviruses was decreased with azithromycin distributions. Clinical Trials Registration. NCT02047981.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciaa606