Different effects of total flavonoids from Arachniodes exilis on human umbilical cord mesenchymal stem cells in vitro

Traditional Chinese medicines are used in promotion of fractured bone healing and bone diseases. Some studies reported total flavonoids from plant can be used as an auxiliary source of exogenous.Use different methods to identify and verify effects of total flavonoids from Arachniodes exilis (TFAE) o...

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Veröffentlicht in:	Medicine (Baltimore) 2020-06, Vol.99 (25), p.e20628-e20628
Hauptverfasser:	Yu, Wenmin, Hu, Wenlong, Ke, Xiumei, Zhou, Xufeng, Yin, Changchang, Yin, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Differentiation - drug effects Cells, Cultured Flavonoids - pharmacology Humans In Vitro Techniques Medicine, Chinese Traditional Mesenchymal Stem Cells - drug effects Observational Study Osteogenesis - drug effects Plant Extracts - pharmacology Plants, Medicinal - chemistry Umbilical Cord - cytology
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Zusammenfassung:	Traditional Chinese medicines are used in promotion of fractured bone healing and bone diseases. Some studies reported total flavonoids from plant can be used as an auxiliary source of exogenous.Use different methods to identify and verify effects of total flavonoids from Arachniodes exilis (TFAE) on human umbilical cord mesenchymal stem cells (HUCMSCs) in vitro.Concentrations of 1 and 5 μg/mL TFAE significantly increased ALPase activity in HUCMSCs compared to the other concentrations at days 3 and 7 (P
ISSN:	0025-7974 1536-5964
DOI:	10.1097/MD.0000000000020628