Volumetric assessment of apparent diffusion coefficient predicts outcome following chemoradiation for cervical cancer

•90th% ADC of tumor on MRI significantly predicts PFS and DMFS in cervical cancer patients treated with CRT.•Overall survival, PFS, and DMFS were worse in patients with 90th percentile ADC 

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Bibliographische Detailangaben
Veröffentlicht in:	Radiotherapy and oncology 2019-06, Vol.135, p.58-64
Hauptverfasser:	Ho, Jennifer C., Fang, Penny, Cardenas, Carlos E., Mohamed, Abdallah S.R., Fuller, Clifton D., Allen, Pamela K., Bhosale, Priya R., Frumovitz, Michael M., Jhingran, Anuja, Klopp, Ann H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Apparent diffusion coefficient Cervical cancer Chemoradiation Chemoradiotherapy Diffusion Magnetic Resonance Imaging - methods Diffusion weighted imaging Disease-Free Survival Female Fluorodeoxyglucose F18 Humans Middle Aged Neoplasm Recurrence, Local - diagnostic imaging Positron Emission Tomography Computed Tomography Positron-Emission Tomography - methods Predictive Value of Tests Prognosis Proportional Hazards Models Retrospective Studies Uterine Cervical Neoplasms - diagnostic imaging Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - therapy
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Beschreibung
Zusammenfassung:	•90th% ADC of tumor on MRI significantly predicts PFS and DMFS in cervical cancer patients treated with CRT.•Overall survival, PFS, and DMFS were worse in patients with 90th percentile ADC
ISSN:	0167-8140 1879-0887 1879-0887
DOI:	10.1016/j.radonc.2019.02.012