Clinical and Practice Variations in Pediatric Acute Recurrent or Chronic Pancreatitis: Report From the INSPPIRE Study

OBJECTIVE:The aim of the study was to determine whether clinical characteristics and management of pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) differ across INSPPIRE (INternational Study Group of Pediatric PancreatitisIn Search for a cuRE) sites. STUDY DESIGN:Data were...

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Veröffentlicht in:Journal of pediatric gastroenterology and nutrition 2020-07, Vol.71 (1), p.112-118
Hauptverfasser: Dike, Chinenye R., Zimmerman, Bridget, Zheng, Yuhua, Wilschanski, Michael, Werlin, Steven L., Troendle, David, Shah, Uzma, Schwarzenberg, Sarah Jane, Pohl, John, Perito, Emily R., Ooi, Chee Y., Nathan, Jaimie D., Morinville, Veronique D., McFerron, Brian, Mascarenhas, Maria, Maqbool, Asim, Liu, Quin, Lin, Tom K., Husain, Sohail Z., Heyman, Melvin B., Gonska, Tanja, Giefer, Matthew J., Gariepy, Cheryl E., Fishman, Douglas S., Bellin, Melena, Barth, Bradley, Abu-El-Haija, Maisam, Lowe, Mark E., Uc, Aliye
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Sprache:eng
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Zusammenfassung:OBJECTIVE:The aim of the study was to determine whether clinical characteristics and management of pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) differ across INSPPIRE (INternational Study Group of Pediatric PancreatitisIn Search for a cuRE) sites. STUDY DESIGN:Data were collected from INSPPIRE and analyzed per US regions and “non-US” sites. Between-group differences were compared by Pearson chi-square test. Differences in disease burden were compared by Kruskal-Wallis test. RESULTS:Out of the 479 subjects, 121 (25%) were enrolled in West, 151 (32%) Midwest, 45 Northeast (9%), 78 (16%) South, and 84 (18%) at non-US sites. Hispanic ethnicity was more common in South (P 
ISSN:0277-2116
1536-4801
DOI:10.1097/MPG.0000000000002661