Modeling opportunities in comparative oncology for drug development

Successful development of novel cancer drugs depends on well-reasoned scientific drug discovery, rigorous preclinical development, and carefully conceived clinical trials. Failure in any of these steps contributes to poor rates of approval for new drugs to treat cancer. As technological and scientif...

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Veröffentlicht in:	ILAR journal 2010, Vol.51 (3), p.214-220
Hauptverfasser:	Gordon, Ira K, Khanna, Chand
Format:	Artikel
Sprache:	eng
Schlagworte:	animal diseases animal models Animals Antineoplastic Agents - therapeutic use chemotherapy Disease Models, Animal Dogs Drug Discovery - methods drug evaluation drug therapy human diseases Humans in vitro studies literature reviews medicine mice neoplasms Neoplasms - drug therapy new drugs One Health preclinical models species differences validity veterinary medicine
Online-Zugang:	Volltext
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