Influenza virus glycoprotein-reactive human monoclonal antibodies

Influenza continues to be a significant public health challenge. Two glycoproteins on the surface of influenza virus, hemagglutinin and neuraminidase, play a prominent role in the process of influenza virus infection and release. Monoclonal antibodies targeting glycoproteins can effectively prevent...

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Veröffentlicht in:	Microbes and infection 2020-07, Vol.22 (6-7), p.263-271
Hauptverfasser:	Li, Yanbai, Wang, Lili, Si, Helong, Yu, Zhengsen, Tian, Shijun, Xiang, Rong, Deng, Xiaoqian, Liang, Ruiying, Jiang, Shibo, Yu, Fei
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibodies, Monoclonal - therapeutic use Antibodies, Neutralizing - immunology Antibodies, Neutralizing - therapeutic use Epitopes Glycoproteins Hemagglutinin Hemagglutinin Glycoproteins, Influenza Virus - chemistry Hemagglutinin Glycoproteins, Influenza Virus - immunology Hemagglutinin Glycoproteins, Influenza Virus - metabolism Humans Influenza A virus Influenza A virus - immunology Influenza B virus Influenza B virus - immunology Monoclonal antibodies Neuraminidase Neuraminidase - chemistry Neuraminidase - immunology Neuraminidase - metabolism Orthomyxoviridae Infections - therapy Orthomyxoviridae Infections - virology
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