Respiratory Pathophysiology of Mechanically Ventilated Patients with COVID-19: A Cohort Study

A cohort study on the respiratory pathophysiology of mechanically ventilated patients with Covid-19, is investigated. Mortality rates between 26% and 61.5% of hospitalized patients with acute respiratory syndrome coronavirus 2 2 (SARS-CoV-2 infection are admitted to the intensive care unit (ICU) are managed with invasive mechanical ventilation. Reports of preserved respiratory system mechanics despite severe hypoxemia in early small series have led some investigators to hypothesize that a significant proportion of Covid-19 respiratory failure is not the typical acute respiratory distress syndrome (ARDS) and warrants alternative management. An overview on the methods, results and characterization of the Covid-19 respiratory failure, is also provided.