Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post–allogeneic hematopoietic stem cell transplant patient

Interleukin-15 superagonist (N-803) treatment of PML and JCV in a post–allogeneic hematopoietic stem cell transplant patient

•Therapy with an IL-15 superagonist resulted in immune and clinical responses in a transplant recipient with PML.

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Bibliographische Detailangaben
Veröffentlicht in:Blood advances 2020-06, Vol.4 (11), p.2387-2391
Hauptverfasser: Oza, Aabha, Rettig, Michael P., Powell, Phil, O'Brien, Kathryn, Clifford, David B., Ritchey, Julie, Gehrs, Leah, Hollaway, Julia, Major, Eugene, Fehniger, Todd A., Miller, Christopher A., Soon-Shiong, Patrick, Rock, Amy, DiPersio, John F.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Exceptional Case Report
Hematopoietic Stem Cell Transplantation
Humans
Immunosuppression
Interleukin-15 - antagonists & inhibitors
JC Virus
Leukoencephalopathy, Progressive Multifocal - etiology
Leukoencephalopathy, Progressive Multifocal - therapy
Male
United States
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Zusammenfassung:•Therapy with an IL-15 superagonist resulted in immune and clinical responses in a transplant recipient with PML.
ISSN:2473-9529
2473-9537
DOI:10.1182/bloodadvances.2019000664