Comparison between quantitative cardiac magnetic resonance perfusion imaging and [15O]H2O positron emission tomography

Purpose To compare cardiac magnetic resonance imaging (CMR) with [ 15 O]H 2 O positron emission tomography (PET) for quantification of absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR) in patients with coronary artery disease (CAD). Methods Fifty-nine patients with stable CAD underwent CMR and [ 15 O]H 2 O PET. The CMR imaging protocol included late gadolinium enhancement to rule out presence of scar tissue and perfusion imaging using a dual sequence, single bolus technique. Absolute MBF was determined for the three main vascular territories at rest and during vasodilator stress. Results CMR measurements of regional stress MBF and MFR showed only moderate correlation to those obtained using PET ( r = 0.39; P