Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia

Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia

Objective To determine the relationship between interventricular septal position (SP) and right ventricular systolic pressure (RVSP) and mortality in infants with severe BPD (sBPD). Study design Infants with sBPD in the Children’s Hospitals Neonatal Database who had echocardiograms 34–44 weeks’ post...

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Veröffentlicht in:Journal of perinatology 2020-01, Vol.40 (1), p.149-156
Hauptverfasser: Vyas-Read, Shilpa, Wymore, Erica M., Zaniletti, Isabella, Murthy, Karna, Padula, Michael A., Truog, William E., Engle, William A., Savani, Rashmin C., Yallapragada, Sushmita, Logan, J. Wells, Zhang, Huayan, Hysinger, Erik B., Grover, Theresa R., Natarajan, Girija, Nelin, Leif D., Porta, Nicolas F. M., Potoka, Karin P., DiGeronimo, Robert, Lagatta, Joanne M.
Format: Artikel
Sprache:eng
Schlagworte:
692/308/409
692/699/1785
Age
Analysis
Babies
Blood Pressure
Bronchopulmonary Dysplasia - diagnostic imaging
Bronchopulmonary Dysplasia - mortality
Dysplasia
Echocardiography
Female
Health aspects
Heart Septal Defects, Ventricular - diagnostic imaging
Hospital Mortality
Hospitals
Humans
Hypertension
Infant mortality
Infant, Newborn
Infant, Premature
Infants
Infants (Newborn)
Intensive Care Units, Neonatal
Lung diseases
Male
Medicine
Medicine & Public Health
Mortality
Pediatric Surgery
Pediatrics
Prognosis
Truog, William E
Ultrasonic imaging
Ventilators
Ventricular Septum - anatomy & histology
Ventricular Septum - diagnostic imaging
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Zusammenfassung:Objective To determine the relationship between interventricular septal position (SP) and right ventricular systolic pressure (RVSP) and mortality in infants with severe BPD (sBPD). Study design Infants with sBPD in the Children’s Hospitals Neonatal Database who had echocardiograms 34–44 weeks’ postmenstrual age (PMA) were included. SP and RVSP were categorized normal, abnormal (flattened/bowed SP or RVSP > 40 mmHg) or missing. Results Of 1157 infants, 115 infants (10%) died. Abnormal SP or RVSP increased mortality (SP 19% vs. 8% normal/missing, RVSP 20% vs. 9% normal/missing, both p  
ISSN:0743-8346
1476-5543
DOI:10.1038/s41372-019-0508-5