Rational Vaccine Design in the Time of COVID-19

As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term "rational vaccine design." We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses includin...

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Veröffentlicht in:Cell host & microbe 2020-05, Vol.27 (5), p.695-698
Hauptverfasser: Burton, Dennis R, Walker, Laura M
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container_title Cell host & microbe
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creator Burton, Dennis R
Walker, Laura M
description As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term "rational vaccine design." We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses including HIV and influenza, as well as coronaviruses.
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subjects AIDS Vaccines - immunology
AIDS Vaccines - standards
Antibodies, Viral - immunology
Antigens, Viral - immunology
Betacoronavirus - immunology
Coronavirus Infections - immunology
Coronavirus Infections - prevention & control
COVID-19
COVID-19 Vaccines
Forum
Humans
Influenza Vaccines - immunology
Influenza Vaccines - standards
Pandemics - prevention & control
Pneumonia, Viral - immunology
Pneumonia, Viral - prevention & control
Research Design - trends
SARS-CoV-2
Viral Vaccines - immunology
title Rational Vaccine Design in the Time of COVID-19
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