Rational Vaccine Design in the Time of COVID-19

As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term "rational vaccine design." We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses includin...

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Veröffentlicht in:Cell host & microbe 2020-05, Vol.27 (5), p.695-698
Hauptverfasser: Burton, Dennis R, Walker, Laura M
Format: Artikel
Sprache:eng
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Zusammenfassung:As scientists consider SARS-CoV-2 vaccine design, we discuss problems that may be encountered and how to tackle them by what we term "rational vaccine design." We further discuss approaches to pan-coronavirus vaccines. We draw on experiences from recent research on several viruses including HIV and influenza, as well as coronaviruses.
ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2020.04.022