MON-584 Albuminuria and Obesity - Which Are the Associated Factors?

Introduction The association between obesity and renal dysfunction has been widely studied. Albuminuria is a cardiovascular risk factor and the most prevalent marker of kidney injury in people with obesity. Despite the higher prevalence of hypertension and diabetes in those patients, other contribut...

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Veröffentlicht in:Journal of the Endocrine Society 2020-05, Vol.4 (Supplement_1)
Hauptverfasser: Costa, Cláudia Fernandes, Salazar, Cristina Daniela, Ferreira, Maria João Silva, Pedro, Jorge Pires, Neves, João Sérgio, Maia, Isabel, Gonçalves, Vanessa Guerreiro, Canha, Marta, Viana, Sara, Silva, Maria Manuel, Mendonça, Fernando, Cabral, Pedro, Lourenço, Rita, Meira, Patrícia, Belo, Sandra, Varela, Ana, Lau, Eva, Oliveira, Joana, Santos, Ana Paula, Torres, Isabel, Freitas, Paula, Carvalho, Davide M
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Sprache:eng
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Zusammenfassung:Introduction The association between obesity and renal dysfunction has been widely studied. Albuminuria is a cardiovascular risk factor and the most prevalent marker of kidney injury in people with obesity. Despite the higher prevalence of hypertension and diabetes in those patients, other contributing factors are still unknown. We aimed to explore the factors related to albuminuria in obesity, analyzing its variation after bariatric surgery. Methods We evaluated 2518 patients undergoing bariatric surgery, of those, 1243 with preoperative albuminuria measurement were included in this study. Albuminuria was determined by the albumin-creatinine ratio (RAC) in an occasional urine sample (mg/g) or by the 24-hour urine albumin excretion rate (TEA) (mg/24h). Means and medians were compared using Student’s T-test or Mann-Whitney tests, respectively. Spearman correlation was used. Results Age (ρ = 0.073; p = 0.010), body mass index (BMI) (ρ = 0.139; p
ISSN:2472-1972
2472-1972
DOI:10.1210/jendso/bvaa046.246