Plasmapheresis treatment in COVID-19–related autoimmune meningoencephalitis: Case series

•COVID-19 patients failing to regain consciousness require neurological assessment.•Brain imaging and lumbar puncture are required to determine CNS involvement.•Neurological involvement during COVID-19 infection can be immune mediated.•Plasmapheresis can be beneficial in COVID-19 patients with autoimmune encephalitis. Severe SARS-CoV-2 (COVID-19) infection has the potential for a high mortality rate. In this paper, we report the results of plasmapheresis treatment in a series of severely ill patients with COVID-19–related autoimmune meningoencephalitis in the Intensive Care Unit (ICU).