Characterizing the BCR repertoire in immune-mediated diseases

Characterizing the BCR repertoire in immune-mediated diseases

B cells can assume protective or pathogenic roles in immune-mediated diseases (IMDs). Analysis of the B cell receptor (BCR) repertoires in six IMDs provides insights into the diversity of B cell repertoires across diseases as well as into potential pathological mechanisms and the effects of differen...

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Veröffentlicht in:Nature reviews. Rheumatology 2020-01, Vol.16 (1), p.7-8
Hauptverfasser: Ramadoss, Nitya S., Robinson, William H.
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Sprache:eng
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631/250/1619/40
631/250/38
692/420/2780
Antigens
B cells
B-cell receptor
B-Lymphocytes
Belimumab
Humans
Immune System Diseases
Lymphocytes B
Medicine
Medicine & Public Health
News & Views
news-and-views
Receptors, Antigen, B-Cell
Rheumatology
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container_title Nature reviews. Rheumatology
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creator Ramadoss, Nitya S.
Robinson, William H.
description B cells can assume protective or pathogenic roles in immune-mediated diseases (IMDs). Analysis of the B cell receptor (BCR) repertoires in six IMDs provides insights into the diversity of B cell repertoires across diseases as well as into potential pathological mechanisms and the effects of different treatments.
doi_str_mv 10.1038/s41584-019-0339-y
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subjects 631/250/1619/40
631/250/38
692/420/2780
Antigens
B cells
B-cell receptor
B-Lymphocytes
Belimumab
Humans
Immune System Diseases
Lymphocytes B
Medicine
Medicine & Public Health
News & Views
news-and-views
Receptors, Antigen, B-Cell
Rheumatology
title Characterizing the BCR repertoire in immune-mediated diseases
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