Prognostication in severe acute respiratory syndrome: A retrospective time-course analysis of 1312 laboratory-confirmed patients in Hong Kong

Background and objective:  The temporal importance of prognostic indicators for severe acute respiratory syndrome (SARS) has not been studied. This study identified the various clinical prognostic factors for SARS and described the temporal evolution of these factors in the course of the SARS illnes...

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Veröffentlicht in:Respirology (Carlton, Vic.) Vic.), 2007-07, Vol.12 (4), p.531-542
Hauptverfasser: CHAN, Jane C.K., TSUI, Eva L.H., WONG, Vivian C.W.
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Sprache:eng
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Zusammenfassung:Background and objective:  The temporal importance of prognostic indicators for severe acute respiratory syndrome (SARS) has not been studied. This study identified the various clinical prognostic factors for SARS and described the temporal evolution of these factors in the course of the SARS illness in Hong Kong in 2003. Methods:  A retrospective analysis of the entire Hong Kong cohort of 1312 laboratory‐confirmed SARS patients aged 15–74 years was undertaken. Demographic, clinical and laboratory data at presentation and investigative data during the first 10 days of illness from the time of symptom onset were compiled. Two adverse outcomes were examined: hospital mortality and the development of oxygenation failure based on the estimated PaO2/FiO2 ratio of
ISSN:1323-7799
1440-1843
DOI:10.1111/j.1440-1843.2007.01102.x