miR-566 expression and immune changes in patients with intracranial aneurysm
Our study aims to investigate the correlations of micro ribonucleic acid (miR)-566 expression with the changes in immune-related indexes and differential genes in patients with intracranial aneurysm (IA). Aneurysm wall tissues from a total of 50 IA cases and the corresponding normal arterial wall ti...
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| Veröffentlicht in: | International journal of clinical and experimental pathology 2020, Vol.13 (4), p.685-691 |
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| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
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| Zusammenfassung: | Our study aims to investigate the correlations of micro ribonucleic acid (miR)-566 expression with the changes in immune-related indexes and differential genes in patients with intracranial aneurysm (IA).
Aneurysm wall tissues from a total of 50 IA cases and the corresponding normal arterial wall tissues from 50 individuals were selected. The miR-566 expression, differential gene expression profile, and expression level of differential gene proteins were detected and analyzed by fluorescence quantitative polymerase chain reaction (qPCR), RNAseq technique and western blotting, respectively.
The miR-566 level was significantly higher in intracranial aneurysm tissues than that in normal arterial wall tissues ( |
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| ISSN: | 1936-2625 |