Understanding infectious agents from an in silico perspective

Knowledge of infectious diseases now emerging from genomic, proteomic, epidemiological and clinical data can provide insights into the mechanisms of immune function, disease pathogenesis and epidemiology. Here, we describe how considerable advances in computational methods of data mining, mathematic...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug discovery today 2011-01, Vol.16 (1), p.42-49
Hauptverfasser:	Tong, Joo Chuan, Ng, Lisa F.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Communicable Diseases - epidemiology Communicable Diseases - genetics Communicable Diseases - microbiology Data Mining - methods Epidemics Epidemiologic Methods General pharmacology Humans Medical sciences Models, Biological Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Knowledge of infectious diseases now emerging from genomic, proteomic, epidemiological and clinical data can provide insights into the mechanisms of immune function, disease pathogenesis and epidemiology. Here, we describe how considerable advances in computational methods of data mining, mathematical modeling in epidemiology and simulation have been used to enhance our understanding of infectious agents and discuss their impact on the discovery of new therapeutics and controlling their spread.
ISSN:	1359-6446 1878-5832
DOI:	10.1016/j.drudis.2010.10.007