Similar prevalence of hepatic steatosis among patients with chronic hepatitis C with and without HIV coinfection

Hepatic steatosis (HS) is frequently observed in HIV-infected patients. It is not known whether HIV infection is an independent risk factor for HS development. We aimed to analyze whether HIV coinfection was associated with a higher frequency of HS in patients with chronic hepatitis C. This was a re...

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Veröffentlicht in:Scientific reports 2020-04, Vol.10 (1), p.6736-6736, Article 6736
Hauptverfasser: Fernandez-Fuertes, M., Macías, J., Corma-Gómez, A., Rincón, P., Merchante, N., Gómez-Mateos, J., Pineda, J. A., Real, L. M.
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Sprache:eng
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Zusammenfassung:Hepatic steatosis (HS) is frequently observed in HIV-infected patients. It is not known whether HIV infection is an independent risk factor for HS development. We aimed to analyze whether HIV coinfection was associated with a higher frequency of HS in patients with chronic hepatitis C. This was a retrospective cross-sectional study. 574 subjects with chronic hepatitis C virus (HCV) infection were included, 246 (43%) of them coinfected with HIV. All of them underwent transient elastography with controlled attenuation parameter (CAP) measurement. HS was defined as CAP ≥ 248 dB/m. 147 individuals (45%) showed HS in the HCV-monoinfected group and 100 (40.7%) in the HIV/HCV-coinfected group (p = 0.318). HS was associated with body mass index (BMI) [
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-020-62671-y