Evaluation of xTAG Respiratory Viral Panel FAST and xTAG Human Parainfluenza Virus Analyte-Specific Reagents for detection of human parainfluenza viruses in respiratory specimens

Evaluation of xTAG Respiratory Viral Panel FAST and xTAG Human Parainfluenza Virus Analyte-Specific Reagents for detection of human parainfluenza viruses in respiratory specimens

Abstract The multiplex xTAG® Respiratory Viral Panel FAST (RVP FAST) research-use-only assay and xTAG® Human Parainfluenza Virus Analyte-Specific Reagent (HPIV-ASR) assay were evaluated with 99 culture-confirmed human parainfluenza virus (HPIV)–positive and –negative specimens and found to have anal...

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Veröffentlicht in:Diagnostic microbiology and infectious disease 2012-03, Vol.72 (3), p.278-281
Hauptverfasser: Selvaraju, Suresh B, Selvarangan, Rangaraj
Format: Artikel
Sprache:eng
Schlagworte:
Analyte-specific reagents
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Human parainfluenza viruses
Humans
Infectious Disease
Infectious diseases
Internal Medicine
Medical sciences
Microbiology
Miscellaneous
Paramyxoviridae - genetics
Paramyxoviridae - isolation & purification
Paramyxoviridae Infections - diagnosis
Reagent Kits, Diagnostic
Reproducibility of Results
Respiratory System - virology
Respiratory viruses
Sensitivity and Specificity
Virology
xTAG Human Parainfluenza Virus ASR
xTAG RVP FAST
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Zusammenfassung:Abstract The multiplex xTAG® Respiratory Viral Panel FAST (RVP FAST) research-use-only assay and xTAG® Human Parainfluenza Virus Analyte-Specific Reagent (HPIV-ASR) assay were evaluated with 99 culture-confirmed human parainfluenza virus (HPIV)–positive and –negative specimens and found to have analytical sensitivities of 95.2% and 100% and specificities of 98.3% and 96.6%, respectively. Since the in vitro diagnostic (IVD) version of the RVP FAST assay does not include HPIVs, the HPIV-ASR assay can be tested in parallel with RVP FAST-IVD for optimal detection of HPIVs.
ISSN:0732-8893
1879-0070
DOI:10.1016/j.diagmicrobio.2011.11.005