Distribution of IFITM3 polymorphism (dbSNP: rs12252) in mestizo populations in four states of Mexico

Distribution of IFITM3 polymorphism (dbSNP: rs12252) in mestizo populations in four states of Mexico

Summary Interferon‐inducible transmembrane protein 3 (IFITM3) participates in the defense against viral infections. This study identified and compared the frequency of the IFITM3 rs12252 polymorphism in 410 individuals in western Mexico. The western Mexican allelic frequencies (frequency of the “C”...

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Veröffentlicht in:International journal of immunogenetics 2018-06, Vol.45 (3), p.146-151
Hauptverfasser: López‐Jiménez, J. J., Peña‐Iñiguez, D. I., Fletes‐Rayas, A. L., Flores‐Martínez, S. E., Sánchez‐Corona, J., Rosales‐Gomez, R. C., Montoya‐Fuentes, H.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Alleles
disease susceptibility
Ethnic Groups - genetics
Gene Frequency
Genetic Predisposition to Disease
Genotype
Healthy Volunteers
Humans
immunity
innate
Interferon
Membrane Proteins - genetics
Mexico
Middle Aged
Polymorphism, Single Nucleotide
Population genetics
Population Studies
RNA-Binding Proteins - genetics
Short Communication
Young Adult
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Zusammenfassung:Summary Interferon‐inducible transmembrane protein 3 (IFITM3) participates in the defense against viral infections. This study identified and compared the frequency of the IFITM3 rs12252 polymorphism in 410 individuals in western Mexico. The western Mexican allelic frequencies (frequency of the “C” allele = 0.18) differ from some American, East Asian and European populations.
ISSN:1744-3121
1744-313X
DOI:10.1111/iji.12361